Zylkene

Zylkene is available as oral capsules in various strengths, designed to facilitate administration to dogs and cats.

The product formulation is hypoallergenic and contains no lactose or preservatives, making it suitable even for animals with digestive sensitivities or food intolerances.

Zylkene for dogs and cats is recommended for dogs and cats in situations where the animals are experiencing stress or difficulty adapting to changes in their environment or routine. These situations may include moving to a new home, introducing a new pet into the family, a change of owner, or periods of separation from the owner.

The product is also frequently used prior to stressful events, such as transport, travel, shows, visits to the vet’s surgery or grooming procedures. In these circumstances, administering the supplement may help reduce signs of anxiety, such as excessive vocalisation, agitation, destructive behaviour or social withdrawal.

Zylkene for cats and dogs is administered orally, once daily, as recommended by the vet and according to the animal’s body weight.

The capsules can be administered directly or their contents can be mixed with the daily food, which makes the product easier to accept. Generally, treatment can be started a few days before an anticipated stressful event or continued for longer periods in cases of persistent stress.

Zylkene for dogs and cats has a very favourable safety profile, and contraindications are limited. However, the product should not be used in animals with known hypersensitivity to milk proteins or to any of the supplement’s components.

In the case of animals with chronic conditions or undergoing complex medical treatment, it is recommended to consult a vet before starting to administer the supplement.

An important aspect of Zylkene is its mechanism of action, which is based on a casein-derived peptide capable of temporarily binding to certain brain receptors involved in regulating emotional state. 

This interaction produces a physiological calming effect without affecting the animal’s learning ability or normal behavioural responses.

According to available data and clinical experience, no significant adverse effects have been associated with the administration of Zylkene. The product is generally well tolerated by both dogs and cats.

In very rare cases, minor digestive reactions, such as mild gastrointestinal discomfort, may occur; however, these symptoms are transient and do not require discontinuation of treatment in most situations.

A major advantage of this supplement is that it can be safely administered alongside other dietary supplements or veterinary medicines. To date, no relevant drug interactions have been reported.

The product can also be administered alongside the animal’s daily feed without affecting the absorption or efficacy of the active ingredient.

Available data indicate that Zylkene has a wide safety margin, and cases of overdose are extremely rare. Even in the event of accidental administration of doses higher than those recommended, no significant toxic effects have been reported.

However, if a very large amount of the product is ingested, it is recommended to monitor the animal and consult a vet.

Zylkene should be stored in its original packaging, in a dry place away from direct light, at moderate temperatures. It is recommended that the product be stored out of reach of children and animals.

Adherence to the storage conditions helps to maintain the stability of the active ingredient and preserve the therapeutic properties of the supplement.

• ScienceDirect, The effects of alpha-casozepine (Zylkene) compared with selegiline hydrochloride (Selgian, Anipryl) on anxiety disorders in dogs
• PubMed, Dietary strategies for reducing stress in pet dogs and cats
• ResearchGate, The efficacy of alpha-casozepine in reducing anxiety in dogs during visits to the vet: a randomised, double-blind, placebo-controlled study
• FAB Clinicians, Overview of behavioural supplements for dogs and cats