Simbiflora

SimbiFlora is available as anoral powder or gastro-resistant capsules, designed to ensure the release of the probiotic content in the intestine, avoiding the destruction of bacterial strains in the acidic gastric environment. Each box contains capsules packaged in blisters, dosed appropriately for daily administration.

SimbiFlora is recommended in the following situations:

• imbalances in the intestinal flora caused by antibiotic treatments;
• recurrent digestive disorders (bloating, abdominal discomfort, irregular transit);
• irritable bowel syndrome;
• immune support during convalescence;
• protection of cells against oxidative stress

SimbiFlora Forte contains a probiotic complex consisting of 8 beneficial bacterial strains, in a total dose of 30 billion CFU per capsule, along with prebiotic fiber, vitamin D3, and zinc. These ingredients work together to balance the intestinal flora, support immunity, and restore the microbiome affected by antibiotics or other imbalances.

For SimbiFlora Forte and SimbiFlora Complex, it is recommended to take one capsule per day, preferably 2 hours after taking an antibiotic.

For SimbiFlora Kids, the dosage can be as follows:

• for children aged 2 to 6 years: 1 sachet per day;
• for children aged 6 to 12 years: 1–2 sachets per day, administered at least 2 hours before or after antibiotics.

The contents of the sachet can be consumed as is or mixed with water, warm drinks (such as tea, milk, juice) or food.

SimbiFlora is not recommended in cases of:

• hypersensitivity to any of the excipients or bacterial strains contained
• severe immunodeficiency or patients with central venous catheters without strict medical supervision
• children under 12 years of age (SimbiFlora Complex and SimbiFlora Forte) or children under 2 years of age (SimbiFlora Kids) without a doctor's approval

It is best to avoid hot drinks immediately after administration. For increased effectiveness, adequate intake of dietary fiber (natural prebiotics) and proper hydration are recommended.

SimbiFlora is suitable for vegetarians and does not contain any potentially allergenic substances.

This product is a dietary supplement and should not be used as a substitute for a varied, balanced diet and a healthy lifestyle.

The product is generally well tolerated. Adverse reactions are rare and include:

• transient bloating or abdominal discomfort in the first few days of administration (due to the adaptation of the intestinal flora);
• minor allergic reactions (skin rash, itching), very rare.

SimbiFlora Forte should be used with caution in combination with digoxin, thiazide diuretics, or other drugs that can increase calcium levels in the blood or urine.

SimbiFlora Complex should be used with caution in people undergoing treatment with anticoagulants, cycloserine, certain antibiotics or lipid-lowering drugs (which lower cholesterol).

It is recommended to consult a doctor before using the supplement.

No cases of overdose with SimbiFlora have been reported. Even in doses higher than those recommended, the product is generally well tolerated, as it is composed of non-pathogenic commensal bacteria. However, in case of excessive consumption, transient digestive symptoms such as flatulence or more frequent stools may occur.

To avoid unpleasant symptoms, it is recommended to follow the recommended daily dose.

SimbiFlora should be stored in its original packaging at a temperature below 25°C, away from light and moisture. The products do not require refrigeration. Keep out of the reach of children and do not use after the expiry date indicated on the packaging.

• PubMed, Lactobacillus spp. for gastrointestinal health: Current and future perspectives
• MDPI, Health benefits of probiotics - a comprehensive review
• PubMed, The role of probiotics in human health
• NIH, Probiotics